Hadassah On Call: New Frontiers in Medicine
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Season
6
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Episode
5

In Sync: Heart & Gut

Ever wonder what your heart's connection is to your gut? Dr. Rabea Asleh, director of the Heart Failure Unit & Cardiovascular Research Center at the Hadassah Medical Organization, discusses the connection and how it influences our immune function and cardiovascular health.

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IN THIS Episode
Guests

Dr. Rabea Asleh

Area of specialty

Cardiology

Heart Failure

Cardiovascular Research

Episode Transcript

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About this episode

Can your gut bacteria influence your heart health? Turns out, they just might! In this episode of Hadassah On Call, we sit down with Dr. Rabea Asleh, director of the Heart Failure Unit and Cardiovascular Research Center at the Hadassah Medical Organization, to explore the surprising link between the microbiome and heart disease — specifically, heart failure with preserved ejection fraction (HFpEF).

HFpEF is one of the most common yet under-recognized forms of heart failure, especially in women, older adults and people with obesity or high blood pressure. Unlike traditional heart failure, where the heart's pumping ability is weakened, HFpEF keeps the heart's function intact but makes it stiffer, leading to fatigue, shortness of breath and swelling. Dr. Asleh's research suggests that gut bacteria might play a key role in the disease's development and progression.

So, what does this mean for your diet, lifestyle and heart health? Could a simple change in your diet help manage or even prevent HFpEF? And what new treatments are on the horizon?

Listen to this episode to take your heart health to the next level.

Further learning:

If you'd like to hear more about heart health, check out previous podcast episodes and Hadassah stories:


Hadassah On Call: New Frontiers in Medicine is a production of Hadassah, The Women's Zionist Organization of America. Hadassah enhances the health of people around the world through medical education, care and research innovations at the Hadassah Medical Organization. For more information on the latest advances in medicine, please head over to hadassah.org.

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The show is hosted by Maayan Hoffman and produced by the team at the Hadassah offices in New York and Israel.

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About our guest(s)

Dr. Rabea Asleh is a clinician-scientist and director of the Heart Failure Unit and Cardiovascular Research Center at the Hadassah Medical Organization. Additionally, he is an associate professor (academic track) in medicine/cardiology at the Hadassah Hebrew University of Jerusalem.

Dr. Asleh completed his PhD in 2006 and MD in 2008 from the Technion Institute of Technology in Israel, graduating summa cum laude. His PhD research focused on the genetic mechanisms linking haptoglobin polymorphism to atherosclerotic cardiovascular disease in diabetic individuals. His work was highly recognized, earning multiple awards and international recognition. He also completed his clinical training in internal medicine and cardiology at Rambam Medical Center. Additionally, he earned a Master of Health Administration (MHA) with excellence from the University of Haifa.

Dr. Asleh has significantly advanced heart failure (HF) care and research at the Hadassah Medical Organization since 2019, establishing the HF Unit as a center of excellence and implementing advanced therapies. As the director of the Cardiovascular Research Center, his research focuses on gut microbiota, HF with preserved ejection fraction (HFpEF), cardiorenal syndrome and myocarditis, with multiple independent grants supporting his work. He holds leadership roles in many professional organizations, and he is dedicated to mentoring young researchers and educating medical students.